{"id":1734,"date":"2021-10-18T12:44:22","date_gmt":"2021-10-18T12:44:22","guid":{"rendered":"https:\/\/www.msd.cz\/cs\/?page_id=1734"},"modified":"2022-02-08T15:18:45","modified_gmt":"2022-02-08T15:18:45","slug":"vyzkum","status":"publish","type":"page","link":"https:\/\/www.msd.cz\/cs\/msd-ceska-republika\/vyzkum\/","title":{"rendered":"V\u00fdzkum"},"content":{"rendered":"
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V\u00fdzkum<\/h2>\n\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n

Kultura v\u011bdeck\u00e9ho b\u00e1d\u00e1n\u00ed, invence a spolupr\u00e1ce<\/h2>\n\n\n\n

Touha po v\u011bdeck\u00e9m pozn\u00e1n\u00ed n\u00e1s motivuje vyv\u00edjet \u0159e\u0161en\u00ed pro ta nejz\u00e1va\u017en\u011bj\u0161\u00ed onemocn\u011bn\u00ed, kter\u00e1 se na sv\u011bt\u011b vyskytuj\u00ed. \u0158ada z t\u011bchto \u0159e\u0161en\u00ed se zrodila v na\u0161ich laborato\u0159\u00edch, kde se zam\u011b\u0159ujeme na objevov\u00e1n\u00ed a v\u00fdvoj nov\u00fdch zp\u016fsob\u016f l\u00e9\u010dby, kter\u00e9 zlep\u0161\u00ed \u017eivoty pacient\u016f.<\/p>\n\n\n\n

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Na\u0161i v\u011bdci<\/h3>\n\n\n\n

Na\u0161i v\u011bdci jsou nad\u0161en\u00fdmi pr\u016fkopn\u00edky ve zkoum\u00e1n\u00ed nov\u00fdch zp\u016fsob\u016f, jak l\u00e9\u010dit zdravotn\u00ed pot\u00ed\u017ee.<\/p>\n<\/div>\n\n\n\n

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Publikace<\/h3>\n\n\n\n

Ka\u017ed\u00fd rok na\u0161i v\u011bdci publikuj\u00ed stovky v\u011bdeck\u00fdch a technick\u00fdch prac\u00ed v p\u0159edn\u00edch recenzovan\u00fdch odborn\u00fdch \u010dasopisech.<\/p>\n<\/div>\n<\/div>\n\n\n

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Nov\u00e9 mo\u017enosti l\u00e9\u010dby a prevence musej\u00ed nejprve proj\u00edt p\u0159\u00edsn\u00fdm procesem klinick\u00e9ho hodnocen\u00ed.<\/h2>\n\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n

D\u011bkujeme<\/h2>\n\n\n\n

Jsme nesm\u00edrn\u011b vd\u011b\u010dn\u00ed tis\u00edc\u016fm dobrovoln\u00edk\u016f, kte\u0159\u00ed se \u00fa\u010dastn\u00ed na\u0161ich klinick\u00fdch hodnocen\u00ed. Jsou to skute\u010dn\u00ed partne\u0159i v na\u0161em v\u00fdzkumu.<\/p>\n\n\n

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Odhodl\u00e1n\u00ed prom\u011b\u0148ovat revolu\u010dn\u00ed v\u011bdeck\u00e9 objevy na inovativn\u00ed mo\u017enosti l\u00e9\u010dby<\/h2>\n\n\t\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/div>\n\n\n
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OBJEV POTENCI\u00c1LN\u00cdCH L\u00c9\u010cIV<\/h3>\n\n\n\n

Ka\u017ed\u00e1 cesta pot\u0159ebuje vizi. Pokud chceme objevit nov\u00e9 zp\u016fsoby l\u00e9\u010dby a nov\u00e9 vakc\u00edny, mus\u00edme nejprve pochopit, jak nemoc funguje.<\/p>\n\n\n\n

Na\u0161i v\u00fdzkumn\u00edci vyu\u017e\u00edvaj\u00ed ty nejmodern\u011bj\u0161\u00ed v\u011bdeck\u00e9 poznatky, kter\u00e9 jim umo\u017e\u0148uj\u00ed zkoumat zdravotn\u00ed pot\u00ed\u017ee ze v\u0161ech mo\u017en\u00fdch \u00fahl\u016f pohledu \u2013 od z\u00e1kladn\u00ed genetick\u00e9 str\u00e1nky onemocn\u011bn\u00ed p\u0159es strukturu jednotliv\u00fdch protein\u016f a\u017e po vztahy mezi stovkami molekul v r\u00e1mci dan\u00e9ho onemocn\u011bn\u00ed.<\/p>\n\n\n\n

Na z\u00e1klad\u011b toho pak mohou v\u011bdci navrhnout, vyvinout a prozkoumat tis\u00edce slou\u010denin nebo vytv\u00e1\u0159et stovky protil\u00e1tek, ze kter\u00fdch z\u00edskaj\u00ed n\u011bkolik slibn\u00fdch potenci\u00e1ln\u00edch l\u00e9\u010div.<\/p>\n<\/div>\n\n\n\n

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PREKLINICK\u00c1 F\u00c1ZE<\/h3>\n\n\n\n

Pokud potenci\u00e1ln\u00ed l\u00e9\u010divo nebo vakc\u00edna \u00fasp\u011b\u0161n\u011b projde procesem klinick\u00e9ho hodnocen\u00ed, v r\u00e1mci kter\u00e9ho se nashrom\u00e1\u017ed\u00ed a zanalyzuje dostate\u010dn\u00e9 mno\u017estv\u00ed dat, m\u016f\u017ee se l\u00e9\u010divo postoupit k posouzen\u00ed p\u0159\u00edslu\u0161n\u00fdmi regula\u010dn\u00edmi org\u00e1ny. Ne\u017e je mo\u017en\u00e9 l\u00e9\u010divo nebo vakc\u00ednu uv\u00e9st na trh a nab\u00eddnout pacient\u016fm, mus\u00ed z\u00edskat schv\u00e1len\u00ed org\u00e1n\u016f, jako je nap\u0159\u00edklad \u010desk\u00fd St\u00e1tn\u00ed \u00fastav pro kontrolu l\u00e9\u010div (S\u00daKL) \u010di americk\u00fd \u00da\u0159ad pro kontrolu potravin a l\u00e9\u010div (FDA, Food and Drug Administration).<\/p>\n\n\n\n

Jen velmi mal\u00e1 \u010d\u00e1st zkouman\u00fdch potenci\u00e1ln\u00edch l\u00e9\u010div \u00fasp\u011b\u0161n\u011b absolvuje p\u0159\u00edsn\u00fd proces v\u00fdzkumu, v\u00fdvoje, klinick\u00e9ho testov\u00e1n\u00ed a regulatorn\u00edho posouzen\u00ed a nakonec se z nich stane schv\u00e1len\u00e9 l\u00e9\u010divo nebo vakc\u00edna.<\/p>\n\n\n\n

Na\u0161e role v oblasti v\u00fdzkumu a v\u00fdvoje pokra\u010duje i po schv\u00e1len\u00ed nov\u00e9ho l\u00e9\u010diva nebo vakc\u00edny \u2013 i nad\u00e1le toti\u017e prov\u00e1d\u00edme pr\u016fb\u011b\u017en\u00e9 monitorov\u00e1n\u00ed a vyhodnocov\u00e1n\u00ed bezpe\u010dnosti, \u00fa\u010dinnosti a hodnoty na\u0161ich v\u00fdrobk\u016f.<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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KLINICK\u00c1 F\u00c1ZE<\/h3>\n\n\n\n

Medicinsk\u00e9ho pokroku lze dos\u00e1hnout pouze prost\u0159ednictv\u00edm klinick\u00fdch hodnocen\u00ed.<\/p>\n\n\n\n

Klinick\u00fdm hodnocen\u00edm se rozum\u00ed v\u00fdzkumn\u00e1 studie na lidsk\u00fdch dobrovoln\u00edc\u00edch, kter\u00e1 testuje nov\u00e9 zp\u016fsoby prevence, odhalov\u00e1n\u00ed, diagnostikov\u00e1n\u00ed \u010di l\u00e9\u010dby r\u016fzn\u00fdch onemocn\u011bn\u00ed. Pom\u00e1haj\u00ed ur\u010dit, zda zkouman\u00e9 vakc\u00edny, l\u00e9\u010diva nebo nov\u00e1 vyu\u017eit\u00ed ji\u017e existuj\u00edc\u00edch l\u00e9\u010div jsou bezpe\u010dn\u00e9 a \u00fa\u010dinn\u00e9.<\/p>\n\n\n\n

Jsme nesm\u00edrn\u011b vd\u011b\u010dn\u00ed tis\u00edc\u016fm dobrovoln\u00edk\u016f, kte\u0159\u00ed se \u00fa\u010dastn\u00ed na\u0161ich klinick\u00fdch hodnocen\u00ed. Jsou to skute\u010dn\u00ed partne\u0159i v na\u0161em v\u00fdzkumu.<\/p>\n<\/div>\n\n\n\n

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POSOUZEN\u00cd REGULA\u010cN\u00cdMI ORG\u00c1NY A PR\u016eB\u011a\u017dN\u00dd MONITORING<\/h3>\n\n\n\n

Ka\u017ed\u00e9 potenci\u00e1ln\u00ed l\u00e9\u010divo projde procesem zdokonalov\u00e1n\u00ed, optimalizace a rozs\u00e1hl\u00e9ho testov\u00e1n\u00ed tak, aby se p\u0159ed zah\u00e1jen\u00edm klinick\u00e9ho testov\u00e1n\u00ed na lidech z\u00edskaly dostate\u010dn\u00e9 v\u011bdeck\u00e9 d\u016fkazy o jeho bezpe\u010dn\u00e9 \u00fa\u010dinnosti.<\/p>\n\n\n\n

Ne\u017e mohou za\u010d\u00edt klinick\u00e1 hodnocen\u00ed, musej\u00ed v\u00fdzkumn\u00e9 t\u00fdmy roz\u0161\u00ed\u0159it v\u00fdrobu a zajistit dostate\u010dnou z\u00e1sobu zkouman\u00e9ho potenci\u00e1ln\u00edho l\u00e9\u010diva pro klinick\u00e9 studie. To znamen\u00e1 roz\u0161\u00ed\u0159en\u00ed v\u00fdroby z mal\u00fdch d\u00e1vek vyr\u00e1b\u011bn\u00fdch v laborato\u0159\u00edch na v\u011bt\u0161\u00ed mno\u017estv\u00ed se slo\u017een\u00edm, kter\u00e9 je vhodn\u00e9 pro klinick\u00e9 vyu\u017eit\u00ed u lid\u00ed.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Kultura v\u011bdeck\u00e9ho b\u00e1d\u00e1n\u00ed, invence a spolupr\u00e1ce Touha po v\u011bdeck\u00e9m pozn\u00e1n\u00ed n\u00e1s motivuje vyv\u00edjet \u0159e\u0161en\u00ed pro ta nejz\u00e1va\u017en\u011bj\u0161\u00ed onemocn\u011bn\u00ed, kter\u00e1 se na sv\u011bt\u011b vyskytuj\u00ed. \u0158ada z t\u011bchto \u0159e\u0161en\u00ed se zrodila v na\u0161ich laborato\u0159\u00edch, kde se zam\u011b\u0159ujeme na objevov\u00e1n\u00ed a v\u00fdvoj nov\u00fdch zp\u016fsob\u016f l\u00e9\u010dby, kter\u00e9 zlep\u0161\u00ed \u017eivoty pacient\u016f. Na\u0161i v\u011bdci Na\u0161i v\u011bdci jsou nad\u0161en\u00fdmi pr\u016fkopn\u00edky ve zkoum\u00e1n\u00ed […]<\/p>\n","protected":false},"author":545,"featured_media":0,"parent":1678,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"bdl_company_name":[],"bdl_item_external_link":[],"editor_notices":[],"footnotes":""},"class_list":["post-1734","page","type-page","status-publish","hentry"],"yoast_head":"\nV\u00fdzkum - MSD \u010cesk\u00e1 republika<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.msd.cz\/cs\/msd-ceska-republika\/vyzkum\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"V\u00fdzkum - MSD \u010cesk\u00e1 republika\" \/>\n<meta property=\"og:description\" content=\"Kultura v\u011bdeck\u00e9ho b\u00e1d\u00e1n\u00ed, invence a spolupr\u00e1ce Touha po v\u011bdeck\u00e9m pozn\u00e1n\u00ed n\u00e1s motivuje vyv\u00edjet \u0159e\u0161en\u00ed pro ta nejz\u00e1va\u017en\u011bj\u0161\u00ed onemocn\u011bn\u00ed, kter\u00e1 se na sv\u011bt\u011b vyskytuj\u00ed. \u0158ada z t\u011bchto \u0159e\u0161en\u00ed se zrodila v na\u0161ich laborato\u0159\u00edch, kde se zam\u011b\u0159ujeme na objevov\u00e1n\u00ed a v\u00fdvoj nov\u00fdch zp\u016fsob\u016f l\u00e9\u010dby, kter\u00e9 zlep\u0161\u00ed \u017eivoty pacient\u016f. 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